diff --git a/gcc/config/i386/serializeintrin.h b/gcc/config/i386/serializeintrin.h
index 89b5b94ea9b..e280250b198 100644
--- a/gcc/config/i386/serializeintrin.h
+++ b/gcc/config/i386/serializeintrin.h
@@ -34,12 +34,7 @@
 #define __DISABLE_SERIALIZE__
 #endif /* __SERIALIZE__ */
 
-extern __inline void
-__attribute__((__gnu_inline__, __always_inline__, __artificial__))
-_serialize (void)
-{
-  __builtin_ia32_serialize ();
-}
+#define _serialize()	__builtin_ia32_serialize ()
 
 #ifdef __DISABLE_SERIALIZE__
 #undef __DISABLE_SERIALIZE__
diff --git a/gcc/testsuite/gcc.target/i386/pr99744-2.c b/gcc/testsuite/gcc.target/i386/pr99744-2.c
new file mode 100644
index 00000000000..9cbefb04536
--- /dev/null
+++ b/gcc/testsuite/gcc.target/i386/pr99744-2.c
@@ -0,0 +1,11 @@
+/* { dg-do compile } */
+/* { dg-options "-O2 -mserialize" } */
+
+#include <x86intrin.h>
+
+__attribute__ ((target("general-regs-only")))
+void
+foo1 (void)
+{
+  _serialize ();
+}