diff --git a/libstdc++-v3/include/std/tuple b/libstdc++-v3/include/std/tuple
index 34d790fd6f5..d3deb7bc124 100644
--- a/libstdc++-v3/include/std/tuple
+++ b/libstdc++-v3/include/std/tuple
@@ -966,12 +966,14 @@ _GLIBCXX_BEGIN_NAMESPACE_VERSION
       : _Inherited()
       { }
 
-      constexpr explicit(!__convertible<const _Elements&...>())
-      tuple(const _Elements&... __elements)
-      noexcept(__nothrow_constructible<const _Elements&...>())
-      requires (__constructible<const _Elements&...>())
-      : _Inherited(__elements...)
-      { }
+      // Defined as a template to work around PR libstdc++/116440.
+      template<typename = void>
+	constexpr explicit(!__convertible<const _Elements&...>())
+	tuple(const _Elements&... __elements)
+	noexcept(__nothrow_constructible<const _Elements&...>())
+	requires (__constructible<const _Elements&...>())
+	: _Inherited(__elements...)
+	{ }
 
       template<typename... _UTypes>
 	requires (__disambiguating_constraint<_UTypes...>())
diff --git a/libstdc++-v3/testsuite/20_util/tuple/116440.C b/libstdc++-v3/testsuite/20_util/tuple/116440.C
new file mode 100644
index 00000000000..12259134d25
--- /dev/null
+++ b/libstdc++-v3/testsuite/20_util/tuple/116440.C
@@ -0,0 +1,29 @@
+// PR libstdc++/116440 - std::tuple<std::tuple<std::any>> does not compile
+// { dg-do compile { target c++17 } }
+
+#include <any>
+#include <tuple>
+#include <type_traits>
+
+template <typename T>
+using TupleTuple = std::tuple<std::tuple<T>>;
+
+struct EmbedAny {
+    std::any content;
+};
+
+static_assert(std::is_copy_constructible<TupleTuple<EmbedAny>>::value);
+static_assert(std::is_move_constructible<TupleTuple<EmbedAny>>::value);
+
+static_assert(std::is_copy_constructible<TupleTuple<std::any>>::value);
+static_assert(std::is_move_constructible<TupleTuple<std::any>>::value);
+
+static_assert(std::is_constructible_v<std::any, TupleTuple<std::any>>);
+
+struct EmbedAnyWithZeroSizeArray {
+    void* pad[0];
+    std::any content;
+};
+
+static_assert(std::is_copy_constructible<TupleTuple<EmbedAnyWithZeroSizeArray>>::value);
+static_assert(std::is_move_constructible<TupleTuple<EmbedAnyWithZeroSizeArray>>::value);