diff --git a/gcc/ChangeLog b/gcc/ChangeLog
index 8a1707b726b..113e3316eb1 100644
--- a/gcc/ChangeLog
+++ b/gcc/ChangeLog
@@ -13,6 +13,9 @@
 	(cris_rtx_costs): Cast argument 2 to rtx_cost to enum rtx_code.
 	(cris_emit_movem_store): Use add_reg_note.
 
+	PR bootstrap/46456
+	* cppbuiltin.c (define_builtin_macros_for_type_sizes): Split assert.
+
 2010-11-12  Eric Botcazou  <ebotcazou@adacore.com>
 
 	* function.c (expand_function_end): Set the locator of the prologue on
diff --git a/gcc/cppbuiltin.c b/gcc/cppbuiltin.c
index 7ac4071c322..7ed6080b201 100644
--- a/gcc/cppbuiltin.c
+++ b/gcc/cppbuiltin.c
@@ -151,7 +151,8 @@ define_builtin_macros_for_type_sizes (cpp_reader *pfile)
   else
     {
       /* Assert that we're only dealing with the PDP11 case.  */
-      gcc_assert (!BYTES_BIG_ENDIAN && WORDS_BIG_ENDIAN);
+      gcc_assert (!BYTES_BIG_ENDIAN);
+      gcc_assert (WORDS_BIG_ENDIAN);
 
       cpp_define (pfile, "__BYTE_ORDER__=__ORDER_PDP_ENDIAN__");
     }